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An estimated 20 million people in the United States suffer from neuropathic pain. ​Peripheral neuropathy is a complex, chronic state that occurs when nerve
fibers are damaged, dysfunctional, or injured, sending incorrect
signals to pain centers in the central nervous system. One of the most common causes of peripheral neuropathy in the U.S. is diabetes.
It is characterized by weakness, pain, and paresthesias that typically begin in the hands or feet and progress proximally. Symptoms depend on the number and types of nerves affected. In
many cases, peripheral neuropathy is idiopathic, but common causes
include diabetes, alcoholism, human immunodeficiency virus (HIV)
infection, and autoimmune disease. Others include toxicity from
chemotherapy and heavy metals.
A team of researchers from Salk
have conducted a revolutionary study, discovering that CBD protects
nerve cells from oxidative damage, a significant driver of cell death.
Medical cannabis doctors are employing novel strategies using cannabinol
to mitigate a range of neurodegenerative diseases.
The cannabinoids
treatments should not only aim to alleviate specific symptoms but also
attempt to delay/arrest disease progression and to repair the damaged
structures.